Department Chemistry and Biochemistry

Professional development course for Chemistry and Biochemistry juniors and seniors. Visiting speakers and in-class workshops expose students to available career paths and research areas, build their professional network, and develop related skills, e.g., communication and personal statement writing.

Professional development course for first year Chemistry majors focusing on information access skills, communication skills, and abilities to discuss ethical situations. Visiting speakers and in-class workshops expose students to available career paths and research areas and build their professional networks.

For non-science majors. The role of chemistry in the production, storage and utilization of energy. Topics covered include basic thermochemistry, thermodynamics, organic chemistry, energy from combustion, electrochemistry, electrochemical energy production, nuclear chemistry, and other sources of energy (phase changes, wind and water power, solar energy, tidal power).

For non-science majors. The experiments which led to the inception and evolution of the concepts of atoms, elements, and molecules will be examined. These samples give a grounding in the fundamentals of chemistry and an understanding of the logic which underlies the "scientific method".

Qualitative and quantitative laboratory experiments which include: the reactions of metals with water; the collection and plotting of data; acid-base titrations; oxidation-reduction titrations; the use of the pH meter and the determination of acid-base titration curves; the use of the spectrophotometer. Coreqs. CHM 1131 or CHM 1151

Students will be required to identify all metal ions present in an unknown solution. Quantitative titrations of sodium carbonate and the total hardness of water. Synthesis of inorganic compounds and determination of the formula of a transition metal complex ion using spectroscopic methods. Corequisites: CHM 1152 or CHM 1156 (Note: Engineering students are waived from this lab.)

Laboratory experiments to accompany CHM 1135, which include: molecular modeling, identification and chemical reactivities of functional groups, reaction kinetic and equilibrium, and acid-base titrations.

Qualitative and quantitative laboratory experiments which include: chemical identification testing, molecular modeling, coordination compound synthesis, reaction kinetics and equilibrium, acid-base titrations, and gas laws Coreq. CHM 1131.

Chemistry of organic and biochemical compounds with an emphasis on the identification and chemical reactivities of functional groups. Students will be required to separate and identify various organic and biochemical compounds. Open to health affiliation students.

Fundamental laws and theories of chemistry: atomic theory, chemical bonding, chemical kinetics and chemical equilibrium, gases, liquids, solids, solutions, stoichiometry, acid-base theories, electrochemical concepts, and an introduction to nuclear chemistry will be included. Open to health affiliation students.

Introduction to organic and biochemistry stressing the application of principles developed in CHM 1131. Open to health affiliation students.

General, Organic and Biological Chemistry concepts foundational to understanding cellular processes. i.e., measurements, atomic structure, nuclear chemistry, chemical bonding, nomenclature and properties of organic functional groups, chemical reactions, solutions, equilibrium, acids and bases, pH, buffers, and structures and functions of carbohydrates, proteins, and lipids.

Basic concepts of chemistry covering the following topics: stoichiometry, redox reactions; properties of gases; thermochemistry; descriptive presentation of atomic orbitals; molecular structure and bonding; chemical trends in the periodic table; properties of bulk matter; colligative properties of solutions.

Continuation of CHM 1151. Introduction to chemical kinetics and equilibrium; the chemistry of acids and bases; buffers and titrations; complex ions and solubility; factors that drive chemical reactions; electrochemistry; nuclear chemistry.

Continuation of CHM 1151. Introduction to chemical kinetics and equilibrium; the chemistry of acids and bases; buffers and titrations; complex ions and solubility; factors that drive chemical reactions; electrochemistry; introduction to organic chemistry.

Selected experiments to illustrate fundamental laboratory techniques and skills. Qualitative and quantitative measurements, synthesis and characterization of inorganic complexes, literature searching and computer usage. Emphasis on modern research applications of metals and main group elements.

Fundamental principles in inorganic chemistry stressing relationships among structure, bonding, and reactivity. Properties of matter, periodic trends, acid/base reactions, redox reactions,and bonding in transition metal complexes.

Laboratory experiments to complement CHM 1512 covering the following: gravimetric analysis, acid-base titrations (weak acid; mixed acid), compleximetric titration and redox reactions.

Chemical analysis, with emphasis upon statistical methods, acid-base properties, pH, equilibrium expressions, complexation equilibria, solubility properties, redox potentials, electrolysis, and electrochemical cells.

Basic concepts of chemistry covering the following topics: stoichiometry, redox reactions; properties of gases; thermochemistry; descriptive presentation of atomic orbitals; molecular structure and bonding; chemical trends in the periodic table; properties of bulk matter; colligative properties of solutions.

Practical experience in techniques used for separation, purification, and isolation of synthetic as well as naturally occurring organic compounds. Semi-micro and micro scale experiments. Crystallization, distillation, extraction, and chromatography are introduced.

Further training in laboratory techniques used in organic chemistry, including those introduced in CHM 2201, and utilization of such techniques in representative types of organic reactions. Semi-micro and micro scale experiments.

Fundamental principles of organic chemistry stressing the relation of structure and reactivity. Structure and bonding; stereochemistry; acids, and bases; electrophilic addition, elimination and nucleophilic substitution.

Continuation of CHM 2211. Carbonyl group reactions, aromatic chemistry, spectroscopy and special topics such as heterocycles, carbohydrates and nucleosides, amino acids and proteins, lipids, radicals, rearrangements, polymers and photochemistry.

Provides practical experience in the principal techniques utilized for the purification, separation, identification, and synthesis of organic compounds on the micro scale. Open to Chemistry majors.

The semi-micro techniques include distillation, recrystallization, extraction, sublimation, and chromatography. Synthesis of representative organic compounds. An introduction to research in organic chemistry, introduction to qualitative organic analysis and practical use of infrared and nuclear magnetic resonance spectroscopies.

Fundamental principles of organic chemistry stressing the relation of structure and reactivity from a physical-chemical viewpoint. Structure and bonding; stereochemistry; acids and bases; electrophilic addition reactions of alkenes, alkynes, and dienes; nucleophilic substitution reactions at saturated carbon atoms and elimination reactions leading to alkenes or alkynes. Open to chemistry majors.

Addition and substitution reactions of carbonyl compounds, electrophilic and nucleophilic aromatic substitutions, radical and concerted reactions, heterocyclic compounds and polymer chemistry. Spectroscopic methods of analysis including nuclear magnetic resonance, infrared spectroscopies and mass spectrometry. Introduction to multi-step organic synthesis. Open to chemistry majors.

This laboratory course emphasizes preparative techniques of inorganic compounds. Instrumental methods of structure elucidation are included.

The second course in the sequence on principles of inorganic chemistry with emphasis on bonding, structure and reactivity. Application of these principles to problems in acid-base, coordination, organometallic, bioinorganic and materials chemistry.

Experimental methods of chemical kinetics will be covered. Spectroscopic, polarimetric, and conductimetric methods will be used.

Experiments centered on chemical thermodynamics including calorimetry and phase equilibria, emphasizing data treatment, including error analysis curve fitting, and related topics.

Experiments on chemical kinetics and optical spectroscopic methods including fluorescence, un-visible, infrared and Raman spectroscopy as well as conductance, viscosity, and numerical analysis of data.

Experiments centered on chemical thermodynamics including calorimetry and phase equilibria, emphasizing data treatment, including error analysis curve fitting, and related topics.

First, second, and third laws of thermodynamics; phase equilibria and chemical equilibria; gases; and electrochemistry will be covered in this course. Corequisite: CHM 3401 or CHM 3403.

This course will present an introduction to quantum mechanics and its implications including molecular orbital theory, electronic structure, and molecular spectroscopy.

First, second, and third laws of thermodynamics; phase equilibria and chemical equilibria; gases; and electrochemistry will be covered in this course.

Chemical kinetics, electrochemistry, and the structure and properties of materials, including atomic structure, solid and liquid state chemistry, surface and colloid chemistry, and transport properties.

A study of thermodynamics, kinetics, chemical equilbria, and spectroscopy as they apply to biological molecules, macromolecules, and cells.

Laboratory techniques to obtain quantitative information about the composition of unknown samples, including potentiometric titration, spectrophotometry, chromatography, kinetic analysis, anodic stipping voltammetry, spectrofluorometry and atomic absorption spectrometry. Designed to complement CHM 3511 lecture.

Laboratory course to complement CHM. 3514; emphasis on the analysis of biological systems utilizing modern analytical techniques. Designed for the biochemistry concentration.

The utilization of instruments covering the following topics: analog and digital signals, absorption and emission of light by molecules and atoms, chromatography (HPLC, GC) and detection, use of enzymes and antibodies, radioactivity, and chemometrics.

Designed for the biochemistry concentration with emphasis on theory, instrumentation and practical applications of analytical chemistry to biological materials.

The currently most useful spectroscopic methods for the structural determination of molecular systems, including: NMR (2D and 2D), mass spectrometry, infrared and ultraviolet-visible spectroscopies.

History and fundamentals of modern Medicinal Chemistry and drug discovery. Drug targets, drug-target relationships: (agonists/antagonists, inhibitors/activators, modulators), structure activity relationships, on-versus off-target relationships, physicochemical properties, pharmacokinetics, bioisosteres, structure- and property-based design. A previous Biochemistry class is suggested but not required.

Survey of organic reactions with emphasis on modern synthetic methods and their applications to the synthesis of complex organic compounds. Enolates, carbonyl condensation reactions, functional group interconversions, electrophilic addition reactions, reductions, organometallic reagents, concerted reations, oxidations. Synthetic strategies including retrosynthetic analysis in the context of specific examples of multi-step synthesis from recent literature.

An expanded presentation of fundamental topics in organic chemistry: structure, bonding, stereochemistry, molecular orbital theory, reactive intermediates and reaction mechanisms.

Examination of the bonding, spectroscopic properties and reactivity of a range of ligands and compleses. Reaction mechanisms and catalytic cycles will be emphasized.

Topics include: step- and chain- polymerizations, copolymerizations, molecular weight determination, polymer morphology, polymer testing and characterization, and current advances in polymer chemistry.

The roles metal ions play in biological systems are explored using relevant examples from natural systems and areas of current research including (but not limited to): catalysis, photosynthesis, respiration, biomimetic modeling, and solar energy conversion.

A study of the interaction of light and matter: excited states, lifetime measurements, photochemistry, lasers and laser spectroscopy.

Basic physicochemical principles of colloids and interfaces such as adhesion, capillarity, interfacial and solution thermodynamics as well as theories of colloidal stability (electrical double layer, zeta potential, DLVO theory), and Light scattering methods.

Focus on basic theories behind popular computational models (e.g., molecular mechanics, density functional theory) and their application to chemical problems.

Apply key concepts in chemistry to global scales by examining chemical systems within Earth's lithosphere, hydrosphere and atmosphere. Examine and discuss natural processes as well as anthropogenic impacts like climate change and environmental contamination using central scientific literature.

Apply key concepts in chemistry to global scales by examining chemical systems within Earth's lithosphere hydrosphere and atmosphere. Examine and discuss natural processes as well as anthropogenic impacts like climate change and environmental contamination using central scientific literature.

An introduction to laboratory techniques in biochemistry; enzyme kinetics, column chromatography, electrophoresis, standard biochemical assays and interpretation of data.

A laboratory course to complement CHM 4621 with emphasis on enzyme purification, enzyme characterization, and nucleic acid analysis.

A continuation of the introduction of fundamental biochemistry laboratory techniques, along with the application of skills acquired in CHM 4603.

A terminal, one semester biochemistry course for the physical sciences and engineers; the kinetics and thermodynamics of biochemical systems and associated molecules, including proteins, nucleic acids, and carbohydrates.

A terminal, one semester survey of biochemistry; carbohydrates, lipids, proteins, nucleic acids, enzymes, vitamins & hormones; consideration of their utilization & metabolism in living systems.

An in depth study of the structure and function of the structure and function of proteins, enzymes, carbohydrates, nucleic acids and lipids.

A study of the metabolism of biomolecules, including carbohydrates, lipids, amino acids and nucleotides, including the integration, regulation and control of intermediary metabolism. Emphasized are the hormonal regulation of pathways and metabolic disease.

Integration of metabolism in organisms, membrane receptors expression of genes, gene manipulation, translation, transcription.

Brief overview of parasitology, the unique biochemistry associated with parasites, discussions of relevant therapeutic applications. The parasites responsible for malaria, toxoplasmosis, trichomoniasis, giardiasis, and African Sleeping Sickness will be studied. The biochemistry of host parasite interaction will also be explored.

The course provides a survey of recent microscopy advances that push the boundaries of image resolution. Instruments and techniques that probe the inner workings of the cell at the level of individual molecules will be discussed, including confocal, TIRF, quantum dots, AFM, and PALM.

A study of the relationship between protein structure and disease, enzymes as therapeutic targets, peptide hormones and obesity, and glucose metabolism and cancer.

Principles, techniques and applications for the large-scale study of proteins, particularly in humans. Mass spectrometry will be covered in detail, and alternative methods and approaches will also be covered.

This course focuses on bioinformatic approaches to studying protein function, structure, and evolution. Other topics will be discussed; for example, genomics and gene expression.

Overview of signal transduction and the biochemistry of receptors and other cell sensors, with an emphasis on oxygen, reactive oxygen species, inflammation, and disease. Current literature will be used, in addition to the textbook.

Structural and mechanistic aspects of enzymes. Topics include chemical catalysis, steady state and pre-steady state kinetics, mechanisms, and biological relevance of specific enzyme systems.

Introduction to the principles and practices of laboratory safety; understanding, recognizing, and communicating laboratory chemical, physical and biological hazards; risk assessment and management of hazards; laboratory accident prevention and safe use of emergency equipment.

Student participation in independent research under faculty supervision, frequent conferences with advisor, on literature search, theoretical and experimental, research.

Student participation in independent research under faculty supervision, frequent conferences with advisor on literature search, theoretical and experimental research.

Continuation of CHM 4801.

Continuation of CHM 4802.

Directed research with a Chemistry or Biochemistry faculty mentor that culminates in a written thesis and seminar presentation. Part I of a two-semester sequence with CHM4852. Permission of participating faculty member required. A written interim report is required at the end of the semester.

Continuation of CHM4851 - Thesis Research I. Directed research with a Chemistry or Biochemistry faculty mentor that culminates in a written thesis and seminar presenation. Permission of participating faculty member required.

Classical and statistical thermodynamics, kinetics, electrochemistry, solid state.

Special Topics: Inorganic Chemistry

A general overview of the chemical industry including the manufacture of basic chemicals, plastics, coatings, paper pulp, surfactants, pesticides, adhesives, etc.

This course examines introductory chemistry topics in a modern and historical light including how the current knowledge of chemistry is owed to Greek philosophers, Islamic healers, Western artisans, monks, and the alchemists. The laboratory recreates chemistry-related activities of the past (e.g., soap and dye-making).

The course explores the chemistry of water including its unique structure and properties, water pollution, water treatment, and its role in biochemistry, climate, renewable energy, and global economic and political policies. The laboratory introduces sampling methods and common quality measurements (e.g., dissolved oxygen and pH).

This course explores the techniques used to preserve and analyze physical evidence and how the results are used in legal proceedings. Topics include crime scene response, ballistics, fingerprinting, drug detection, and DNA analysis The laboratory provides experience with methods used in modern forensic science.

This course provides an understanding of artistic media related to technological advances throughout the centuries. Creating, viewing, and understanding, authenticating, and conserving works of art will be explored. The laboratory provides practice and an appreciation of the advances in artistic media throughout history.

An introduction to the science of energy principles and issues. Lecture and Laboratory provide context and practice with modern examples.

Polymers surround our everyday existence from the clothes we wear to the plastic packaging we use to polymers in wood. Using an interdisciplinary approach, we will study polymer lifecycles to help inform and shape responsible plastic use.

The chemical and biochemical properties of food - sugars, fats, proteins, and mixtures - will be explored. The chemical reactions that occur during food preparation and cooking, and the science behind food preparation will be examined in depth.